Reaction #74317

ord-240c5d7a97db48028804ece083788aab

Reaction equation

NC(=S)NC1CCCCC1
n-cyclohexylthiourea
CCOC(=O)C(Br)CC
ethyl 2-bromobutyrate
→
CCC1SC(NC2CCCCC2)=NC1=O
2-(cyclohexylamino)-5-ethyl-1,3-thiazol-4(5H)-one

Reactants

NC(=S)NC1CCCCC1
n-cyclohexylthiourea
CCOC(=O)C(Br)CC
ethyl 2-bromobutyrate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherSynthesis
  2. 2
    OtherGave 201 mg (75%)

Procedure

Synthesis was performed from n-cyclohexylthiourea and ethyl 2-bromobutyrate according to Method C. Gave 201 mg (75%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09