Reaction #74315

ord-1ef7805e355c4ea1903767c7df1dd78c

Reaction equation

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
CCOC(=O)C(Br)CC
ethyl 2-bromobutyrate
→
CCC1SC(NC2CC3CCC2C3)=NC1=O
2-(bicyclo[2.2.1]hept-2-ylamino)-5-ethyl-1,3-thiazol-4(5H)-one

Reactants

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
CCOC(=O)C(Br)CC
ethyl 2-bromobutyrate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherSynthesis

Procedure

Synthesis was performed from N-bicyclo[2.2.1]hept-2-ylthiourea and ethyl 2-bromobutyrate according to Method C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09