Reaction #72652

Reaction equation

2-chloroquinazolin-4-amine

2-Chloroquinazolin-4-amine

methoxylamine

→

2-(Methoxyamino)quinazolin-4-amine

Conditions

Procedure

Prepared as in Example 42 from 2-chloroquinazolin-4-amine (Example 38) and methoxylamine. 1H NMR (400 MHz, DMSO-d6) δ3.79 (s, 3H), 7.48-7.44 (m, 1H), 7.86-7.80 (m, 2H), 8.27 (d, J=8.0 Hz, 1H), 8.99 (s, 1H), 9.16 (s, 1H), 12.39-12.08 (m, 1H). MS 191 (MH+).

Source