Reaction #71191

ord-eb005836d15941658777c056c8f823a6

Reaction equation

CC1(c2cccc(Cn3ncc(N)n3)c2)OCCO1
2-[3-(2-methyl-[1,3]dioxolan-2-yl)-benzyl]-2H-[1,2,3]triazol-4-ylamine
O=C(O)c1ncoc1-c1ccccc1
5-phenyl-oxazole-4-carboxylic acid
→
CC(=O)c1cccc(Cn2ncc(NC(=O)c3ncoc3-c3ccccc3)n2)c1
5-Phenyl-oxazole-4-carboxylic acid [2-(3-acetyl-benzyl)-2H-[1,2,3]triazol-4-yl]-amide

Reactants

CC1(c2cccc(Cn3ncc(N)n3)c2)OCCO1
2-[3-(2-methyl-[1,3]dioxolan-2-yl)-benzyl]-2H-[1,2,3]triazol-4-ylamine
O=C(O)c1ncoc1-c1ccccc1
5-phenyl-oxazole-4-carboxylic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Following general procedure A followed by B, starting from 2-[3-(2-methyl-[1,3]dioxolan-2-yl)-benzyl]-2H-[1,2,3]triazol-4-ylamine and 5-phenyl-oxazole-4-carboxylic acid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08536209B2uspto-grants-2013_09