Reaction #710566

ord-1fa805510a3a4b09ac2e040fb6cba94a

Reaction equation

O=S(=O)(Cl)c1ccc(Br)cc1
4-bromophenylsulfonyl chloride
COC(=O)[C@H]1CC[C@@H](N)CC1
methyl cis-4-aminocyclohexanecarboxylate
→
COC(=O)[C@H]1CC[C@@H](NS(=O)(=O)c2ccc(Br)cc2)CC1
title compound
COC(=O)[C@H]1CC[C@@H](NS(=O)(=O)c2ccc(Br)cc2)CC1
Methyl 4-(4-bromophenylsulfonamido)cis-cyclohexanecarboxylate

Reactants

O=S(=O)(Cl)c1ccc(Br)cc1
4-bromophenylsulfonyl chloride
COC(=O)[C@H]1CC[C@@H](N)CC1
methyl cis-4-aminocyclohexanecarboxylate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Using a method analogous to Method A with 4-bromophenylsulfonyl chloride and methyl cis-4-aminocyclohexanecarboxylate, the title compound was obtained as a pale brown solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09302984B2uspto-grants-2016_04