Reaction #70283

Reaction equation

2-bromo-5-iodopyridine

methyl 2-amino-5-cyclopropylbenzoate

Cs2CO3

Intermediate 8

methyl 2-amino-5-cyclopropylbenzoate

→

Methyl 2-(6-bromopyridin-3-ylamino)-5-cyclopropylbenzoate

Conditions

Workup

1. 1
   OtherObtained
2. 2
   Other(0.155 g, 43% of yield)

Procedure

Obtained (0.155 g, 43% of yield) following the procedure described in Intermediate 15 starting with methyl 2-amino-5-cyclopropylbenzoate (described in Intermediate 8 (step A)) (1.05 mmol, 0.200 g), 2-bromo-5-iodopyridine (1.05 mmol, 0.297 g) and Cs2CO3 (2.09 mmol, 0.682 g) instead of NaOtBu.

Source