Reaction #70052

Reaction equation

1-(1H-benzo[d]imidazol-5-yl)-4-hydroxy-5-(4-morpholinophenyl)-1H-pyrrol-2(5H)-one

piperidine

→

1-(1H-Benzo[d]imidazol-5-yl)-5-(4-morpholinophenyl)-4-(piperidin-1-yl)-1H-pyrrol-2(5H)-one

Solvents

toluene DMF

Conditions

Workup

1. 1
   OtherThe compound was synthesized

Procedure

The compound was synthesized starting from 1-(1H-benzo[d]imidazol-5-yl)-4-hydroxy-5-(4-morpholinophenyl)-1H-pyrrol-2(5H)-one (0.90 g, 2.4 mmol) and piperidine (4 ml) in toluene/DMF (2:1; 15 ml) according to method 8a described above.

Source