Reaction #696717

ord-36d1ea93fb564ca2a2e770fd879a0244

Reaction equation

N
ammonia
N
ammonia
O=C(O)CNCP(=O)(O)O
glyphosate
→
O=C([O-])CNCP.[NH4+]
ammonium glyphosate
O=C(O)CNCP(=O)(O)O
glyphosate

Reactants

N
ammonia
—
Solution 1
N
ammonia
O=C(O)CNCP(=O)(O)O
glyphosate

Reagents

None

Solvents

O
water
O
water

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherIn a stirred 10 liter round-bottom flask equipped with a water cooled condenser
  2. 2
    Otherthat the temperature of reaction mixture
  3. 3
    Otherdid not exceed 85° C
  4. 4
    Otherwas obtained
  5. 5
    workup.ADDITIONadded

Procedure

In a stirred 10 liter round-bottom flask equipped with a water cooled condenser, thermometer, nitrogen blanket and equilibrating dropping funnel, was charged 500 grams of Solution 1 and 968 grams of water. With stirring, 2409 grams of glyphosate acid in the form of wet cake were added. Then 1623 grams of 25% aqueous ammonia were added at such a rate that the temperature of reaction mixture did not exceed 85° C. The pH of the reaction mixture was measured, and up to 85 grams of 25% aqueous ammonia were added in increments until a pH of 6.3-6.7 was obtained. The assay was determined by high pressure liquid chromatography by standard methods and sufficient additional water added to give an ammonium glyphosate solution with a glyphosate assay of 41.7% a.e. or 525 g a.e./l.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05998332uspto-grants-1999_12