Reaction #676935

ord-41ba914249fb4ce2a675e9151cde0571

Reaction equation

O=S(=O)(Cl)c1cc2ccccc2s1
1-benzothiophene-2-sulfonyl chloride
Nc1cccc(C(=O)O)c1
3-aminobenzoic acid
→
O=C(O)c1cccc(NS(=O)(=O)c2cc3ccccc3s2)c1
title compound
Yield 41.0%
O=C(O)c1cccc(NS(=O)(=O)c2cc3ccccc3s2)c1
3-[(1-Benzothien-2-ylsulfonyl)amino]benzoic acid
Yield 41.0%

Reactants

O=S(=O)(Cl)c1cc2ccccc2s1
1-benzothiophene-2-sulfonyl chloride
Nc1cccc(C(=O)O)c1
3-aminobenzoic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThe product was prepared

Procedure

The product was prepared according to General Procedure 1, described in Example 1, with 1-benzothiophene-2-sulfonyl chloride (12.8 mg, 0.055 mmol) and 3-aminobenzoic acid (6.9 mg, 0.050 mmol). The title compound was obtained in 41% yield (8.9 mg). MS (ESI+) calcd mass for C15H11NO4S2 333.012949, found 333.014269.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09233946B2uspto-grants-2016_01