Reaction #676933

ord-8d7424a95518459c8c92aac0d6afe424

Reaction equation

O=S(=O)(Cl)c1cc2ccccc2s1
1-benzothiophene-2-sulfonyl chloride
Nc1cccc(-c2nnn[nH]2)c1
5-(3-amino-phenyl)tetrazole
→
O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1cc2ccccc2s1
title compound
Yield 60.0%
O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1cc2ccccc2s1
N-[3-(1H-Tetrazol-5-yl)phenyl]-1-benzothiophene-2-sulfonamide
Yield 60.0%

Reactants

O=S(=O)(Cl)c1cc2ccccc2s1
1-benzothiophene-2-sulfonyl chloride
Nc1cccc(-c2nnn[nH]2)c1
5-(3-amino-phenyl)tetrazole

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThe product was prepared

Procedure

The product was prepared according to General Procedure 1, described in Example 1, with 1-benzothiophene-2-sulfonyl chloride (12.8 mg, 0.055 mmol) and 5-(3-amino-phenyl)tetrazole (8.0 mg, 0.050 mmol). The title compound was obtained in 60% yield (10.8 mg). MS (ESI+) calcd mass for C15H11N5O2S2 357.035416, found 357.036256.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09233946B2uspto-grants-2016_01