Reaction #657255

Reaction equation

1-trityl-4-hydroxymethylpyrazole

sodium hydride

iodomethane

→

1-trityl-4-methoxymethylpyrazole

Yield 93.0%

Solvents

tetrahydrofuran

Conditions

Workup

1. 1
   OtherThis compound is obtained

Procedure

This compound is obtained by reacting 1-trityl-4-hydroxymethylpyrazole (555 mg; 1.63 mmol) in dry tetrahydrofuran with sodium hydride (98 mg; 2.44 mmol) and iodomethane (0.5 mL; 8.15 mmol). Yield: 93% (536 mg, 1.51 mmol).

Source