Reaction #64835

ord-65a8d59987b24ee7af10a32aaae06db0

Reaction equation

CCN(CC)c1ccc2cc(C(C)=O)c(=O)oc2c1
3-acetyl-7-diethylaminocoumarin
CC(=O)c1cc2cc3c4c(c2oc1=O)CCCN4CCC3
Coumarin 334
→
CCN(CCN1CCCCC1)c1ccc(C=CC(=O)c2cc3cc4c5c(c3oc2=O)CCCN5CCC4)cc1
10-(3-(N-ethyl-N-(2-piperidinoethyl)-4-aminophenyl)propenoyl)-1H,2H,3H,5H,6H,7H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one

Reactants

CCN(CC)c1ccc2cc(C(C)=O)c(=O)oc2c1
3-acetyl-7-diethylaminocoumarin
CC(=O)c1cc2cc3c4c(c2oc1=O)CCCN4CCC3
Coumarin 334

Reagents

None

Solvents

CCO
ethanol

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

10-(3-(N-ethyl-N-(2-piperidinoethyl)-4-aminophenyl)propenoyl)-1H,2H,3H,5H,6H,7H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one (7) was prepared according to the procedure of Example 3 wherein 3-acetyl-7-diethylaminocoumarin was replaced by Coumarin 334; (Eastman Kodak, Rochester, N.Y.) λmax (ethanol)=503 nm ##STR14##

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05415976uspto-grants-1995_05