Reaction #64698

Reaction equation

formic acid

Meldrum's acid

p-nitrobenzaldehyde

→

3-(4-nitrophenyl)propionic acid

Solvents

triethylamine

Conditions

Workup

1. 1
   Otherprepared
2. 2
   Otherreacted at the same temperature for 1 hour
3. 3
   OtherThe product was isolated

Procedure

3.60 g (0.025 mol) of Meldrum's acid and 3.8 g (0.025 mol) of p-nitrobenzaldehyde were weighed in to 25 ml of the mixture of formic acid and triethylamine prepared as described in Example l. The reaction mixture was heated to 105° C. during 1 hour and reacted at the same temperature for 1 hour. The product was isolated according to Example 1.

Source