Reaction #64598

ord-958d91a3e3b94844878d9825f3955bb5

Reaction equation

CCCCNC
n-butylmethylamine
COC(C)(OC)N(C)C
N,N-dimethylacetamide dimethyl acetal
→
CCCCN(C)C(C)(OC)OC
N-butyl-N-methylacetamide dimethyl acetal

Reactants

CCCCNC
n-butylmethylamine
COC(C)(OC)N(C)C
N,N-dimethylacetamide dimethyl acetal

Reagents

None

Conditions

Temperature
130°CELSIUS
Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    workup.DISTILLATIONSubsequent vacuum distillation

Procedure

6.1 g (0.07 mol) of n-butylmethylamine are stirred with 9.3 g (0.07 mol) of N,N-dimethylacetamide dimethyl acetal for 24 hours under reflux at a bath temperature of 130° C. Subsequent vacuum distillation gives N-butyl-N-methylacetamide dimethyl acetal, bp 72°-75° C./31 mbar.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05413994uspto-grants-1995_05