Reaction #640562

Reaction equation

3-amino phenylboronic acid

acryloyl chloride

→

3-Acrylamido-phenylboronic acid

Conditions

Workup

1. 1
   ExtractionThe product was extracted in acetone
2. 2
   Otherdried
3. 3
   Othera rotary evaporator

Procedure

3-Acrylamido-phenylboronic acid (“3-APB”) was synthesized by reacting 3-amino phenylboronic acid with an excess of acryloyl chloride in an aqueous alkaline solution. The product was extracted in acetone and dried using a rotary evaporator. The structure of 3-APB was confirmed using NMR. The purity was about 90%, TLC showing very little contamination.

Source