Reaction #631993

Reaction equation

Ethyl vinyl ether

6-carbomethoxy-4,4-dimethylcyclohexan-1-ol

→

2-carbomethoxy-4,4-dimethyl-1-(2-methyl-1,3-dioxapent-1-yl)cyclohexane

Yield 98.0%

Solvents

Et2O

Conditions

Workup

1. 1
   WashAfter 30 minutes the mixture was washed with saturated aqueous NaHCO3
2. 2
   workup.DISTILLATIONAfter distillation (Bp 110-120° C./10 torr)

Procedure

Ethyl vinyl ether (10.5 g) were added slowly and dropwise to 50 ml of Et2O containing 6-carbomethoxy-4,4-dimethylcyclohexan-1-ol (25 g) at 0° C. under nitrogen. After 30 minutes the mixture was washed with saturated aqueous NaHCO3. After distillation (Bp 110-120° C./10 torr) were obtained 34 g of 2-carbomethoxy-4,4-dimethyl-1-(2-methyl-1,3-dioxapent-1-yl)cyclohexane (yield 98%)

Source