Reaction #625417

Reaction equation

4-amino-1-methyl-1H-pyrimidin-2-one

1,3-dichloroacetone

2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one

→

2-Chloromethyl-6-methyl-6H-imidazo[1,2-c]pyrimidin-5-one

Conditions

Procedure

2-Chloromethyl-6-methyl-6H-imidazo[1,2-c]pyrimidin-5-one was prepared from 4-amino-1-methyl-1H-pyrimidin-2-one and 1,3-dichloroacetone using the methods described above for the preparation of 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one.

Source