Reaction #625414

ord-0087f7e1c56f48e785f663757a860771

Reaction equation

Nc1cc[nH]c(=O)n1
cytosine
CI
methyliodide
Nc1ccn(Cc2ccccc2)c(=O)n1
4-amino-1-benzyl-1H-pyrimidin-2-one
→
Cn1ccc(N)nc1=O
4-Amino-1-methyl-1H-pyrimidin-2-one

Reactants

Nc1cc[nH]c(=O)n1
cytosine
CI
methyliodide
Nc1ccn(Cc2ccccc2)c(=O)n1
4-amino-1-benzyl-1H-pyrimidin-2-one

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

4-Amino-1-methyl-1H-pyrimidin-2-one was prepared from cytosine and methyliodide using the methods described above for the preparation of 4-amino-1-benzyl-1H-pyrimidin-2-one.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08865725B2uspto-grants-2014_10