Reaction #619120

ord-e300ce33ff7e43d7a7d76c9efd1c84cc

Reaction equation

Cc1nc(NC(=O)N(C2CCCCC2)C2CCCCC2)sc1SC#N
1,1-dicyclohexyl-3-(4-methyl-5-thiocyanato-thiazol-2-yl)-urea
ClCCN1CCCCC1
N-(2-chloroethyl)piperidine
→
Cc1nc(NC(=O)N(C2CCCCC2)C2CCCCC2)sc1SCCN1CCCCC1
1,1-Dicyclohexyl-3-[4-methyl-5-(2-piperidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

Reactants

Cc1nc(NC(=O)N(C2CCCCC2)C2CCCCC2)sc1SC#N
1,1-dicyclohexyl-3-(4-methyl-5-thiocyanato-thiazol-2-yl)-urea
ClCCN1CCCCC1
N-(2-chloroethyl)piperidine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherPrepared

Procedure

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(4-methyl-5-thiocyanato-thiazol-2-yl)-urea and N-(2-chloroethyl)piperidine.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE045183E1uspto-grants-2014_10