Reaction #619089

ord-15abea1ad9c849de8da8748755d13bf9

Reaction equation

CCOC(=O)CCSc1sc(NC(=O)N(C2CCCCC2)C2CCCCC2)nc1C
3-[2-(3,3-dicyclohexyl-ureido)-4-methyl-thiazol-5-yl-sulfanyl]-propionic acid ethyl ester
CCOC(=O)CCSc1sc(N)nc1C
3-(2-amino-4-methyl-thiazol-5-ylsulfanyl)-propionic acid ethyl ester
→
Cc1nc(NC(=O)N(C2CCCCC2)C2CCCCC2)sc1SCCC(=O)O
3-[2-(3,3-Dicyclohexyl-ureido)-4-methyl-thiazol-5-ylsulfanyl]-propionic acid

Reactants

—
( B )
CCOC(=O)CCSc1sc(NC(=O)N(C2CCCCC2)C2CCCCC2)nc1C
3-[2-(3,3-dicyclohexyl-ureido)-4-methyl-thiazol-5-yl-sulfanyl]-propionic acid ethyl ester
CCOC(=O)CCSc1sc(N)nc1C
3-(2-amino-4-methyl-thiazol-5-ylsulfanyl)-propionic acid ethyl ester

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherPrepared

Procedure

Prepared as described in general procedures (A) and (B) using 3-[2-(3,3-dicyclohexyl-ureido)-4-methyl-thiazol-5-yl-sulfanyl]-propionic acid ethyl ester and 3-(2-amino-4-methyl-thiazol-5-ylsulfanyl)-propionic acid ethyl ester

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE045183E1uspto-grants-2014_10