Reaction #619086

ord-f30dac71767a40478a61389dc4a8df84

Reaction equation

O=C(Nc1ncc(Br)s1)N(C1CCCCC1)C1CCCCC1
3-(5-bromo-thiazol-2-yl)-1,1-dicyclohexyl-urea
Cn1ccnc1S
2-mercapto-1-methyl-1H-imidazole
→
Cn1ccnc1Sc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-Dicyclohexyl-3-[5-(1-methyl-1H-imidazol-2-ylsulfanyl)-thiazol-2-yl]-urea

Reactants

O=C(Nc1ncc(Br)s1)N(C1CCCCC1)C1CCCCC1
3-(5-bromo-thiazol-2-yl)-1,1-dicyclohexyl-urea
Cn1ccnc1S
2-mercapto-1-methyl-1H-imidazole

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherPrepared

Procedure

Prepared as described in general procedure (E) using 3-(5-bromo-thiazol-2-yl)-1,1-dicyclohexyl-urea and 2-mercapto-1-methyl-1H-imidazole.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE045183E1uspto-grants-2014_10