Reaction #6077

Reaction equation

(+-)-2-phenyl-3-(1H-imidazol-1-yl)-2,3-dihydro-4H-benzopyran-4-one

hydroxylamine hydrochloride

ethanol

→

(+-)-(Z)-Ethyl-6-[[2-phenyl-3-(1H-imidazol-1-yl)-2,3-dihydro-4H-benzopyranylidene]aminoxy]hexanoate

Solvents

pyridine

Conditions

Workup

1. 1
   Othercan be prepared
2. 2
   workup.ADDITIONis added at room temperature to the solution

Procedure

As an example the intermediate oxime used as starting material can be prepared as follows: (+-)-2-phenyl-3-(1H-imidazol-1-yl)-2,3-dihydro-4H-benzopyran-4-one[J. Het. Chem. 21,311,(1984)], (4 g.; 0.014 moles), is dissolved in pyridine, and hydroxylamine hydrochloride (2.4 g.; 0.034 moles) dissolved in ethanol (20 ml), is added at room temperature to the solution.

Source