Reaction #607463

ord-677df73deb7e4e518b154a85739743fa

Reaction equation

O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
1c
O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl) quinazoline-4 (3H)-one
Cc1cccc(N2CCNCC2)c1C
1-(2,3-dimethylphenyl)piperazine
→
Cc1cccc(N2CCN(CCn3cnc4ccccc4c3=O)CC2)c1C
3-(2-(4-(2,3-dimethylphenyl)piperazine-1-yl)ethyl)quinazoline-4 (3H)-one

Reactants

O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
1c
O=c1c2ccccc2ncn1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1
3-(2-(4-(3-(trifluoromethyl)phenyl)piperazine-1-yl)ethyl) quinazoline-4 (3H)-one
Cc1cccc(N2CCNCC2)c1C
1-(2,3-dimethylphenyl)piperazine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThis compound was prepared in compliance with the procedure

Procedure

This compound was prepared in compliance with the procedure described in 1c, using 1-(2,3-dimethylphenyl)piperazine instead of 1-(3-(trifluoromethyl)phenyl)piperazine.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09326984B2uspto-grants-2016_05