Reaction #607457

ord-125eeb319eaa4ceaaf5d2a511eb3544c

Reaction equation

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
aspartame
CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
Acesulfame-K
O=C1NS(=O)(=O)c2ccccc21.[Na]
sodium saccharin
[Cl-].[Na+]
sodium chloride
[Cl-].[K+]
potassium chloride
O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Na+]
sodium ascorbate
OC[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl
sucralose
→
O=C1O[C@H]([C@@H](O)CO)C(O)=C1O.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Na+]
Sodium Ascorbate Ascorbic Acid

Reactants

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
aspartame
CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
Acesulfame-K
O=C1NS(=O)(=O)c2ccccc21.[Na]
sodium saccharin
—
PEG3350
[Cl-].[Na+]
sodium chloride
[Cl-].[K+]
potassium chloride
O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O.[Na+]
sodium ascorbate
OC[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl
sucralose

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

In an initial set of solutions containing PEG3350 (40 g), sodium chloride (2.8 g), potassium chloride (1.3 g) and sodium ascorbate (56.6 g), it was found that the sweeteners sucralose and aspartame were most effective in reducing the perceived saltiness of the solution. Acesulfame-K and sodium saccharin were less effective.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09326969B2uspto-grants-2016_05