Reaction #607426

ord-9c9b229c37be48a5a3b6c77f2f6d3727

Reaction equation

Cc1ccc(C(N)CCO)cc1
3-amino-3-(p-tolyl)propan-1-ol
FC(F)(F)Oc1ccc(-n2cnc(-c3ccc(N=C=S)cc3)n2)cc1
3-(4-isothiocyanato-phenyl)-1-(4-trifluoromethoxy-phenyl)-1H-1,2,4-triazole
Cc1ccc(C2CCOC(Nc3ccc(-c4ncn(-c5ccc(OC(F)(F)F)cc5)n4)cc3)=N2)cc1
title compound
Cc1ccc(C2CCOC(Nc3ccc(-c4ncn(-c5ccc(OC(F)(F)F)cc5)n4)cc3)=N2)cc1
4-(p-Tolyl)-N-(4-(1-(4-(trifluoromethoxy)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)-5,6-dihydro-4H-1,3-oxazin-2-amine

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared with 3-amino-3-(p-tolyl)propan-1-ol and 3-(4-isothiocyanato-phenyl)-1-(4-trifluoromethoxy-phenyl)-1H-1,2,4-triazole and isolated as an off-white solid (0.020 g, 9%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09326516B2uspto-grants-2016_05