Reaction #601930

ord-3001334b82df4fe38fb9fdc78d4cc755

Reaction equation

NC(=O)Cl
carbamoyl chloride
CC#COCCOCCOCCNCc1ccccc1
amine
CC#COCCOCCOCCNCc1ccccc1
N-Benzyl-2-(2-(2-(Propynyloxy)Ethoxy)Ethoxy)Ethyl Amine
→
CC#COCCOCCOCCN(Cc1ccccc1)C(=O)Cl
N-Benzyl-2-(2-(2-(propynyloxy)ethoxy)ethoxy)ethyl aminocarbonyl chloride

Reactants

NC(=O)Cl
carbamoyl chloride
CC#COCCOCCOCCNCc1ccccc1
amine
CC#COCCOCCOCCNCc1ccccc1
N-Benzyl-2-(2-(2-(Propynyloxy)Ethoxy)Ethoxy)Ethyl Amine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

N-Benzyl-2-(2-(2-(propynyloxy)ethoxy)ethoxy)ethyl aminocarbonyl chloride was prepared from amine 27 (20 mg, 0.072 mmol) following General Procedure 1. The crude carbamoyl chloride was used directly for the next step.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09108930B2uspto-grants-2015_08