Reaction #59912

Reaction equation

( 6f )

2-(((4-((2-methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

1,5-dioxaspiro[5.5]undec-3-ylmethanol

→

title compound

Yield 8.4%

2-(((4-(1,5-dioxaspiro[5.5]undec-3-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

Yield 8.4%

Conditions

Workup

1. 1
   Otherobtained in the step (25a)

Procedure

The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 1,5-dioxaspiro[5.5]undec-3-ylmethanol obtained in the step (25a) to obtain the title compound (125 mg, total yield: 8.4%) as a light yellow solid.

Source