Reaction #58233

ord-42bdeafb19fa4f718e1042462480da8c

Reaction equation

COc1ccc(C(=O)Cl)cc1
4-methoxybenzoyl chloride
Cc1ccc(Br)c(C(=O)O)c1
2-bromo-5-methylbenzoic acid
→
COc1ccc(C(=O)c2ccc(C)cc2C(=O)O)cc1
2-(4-methoxybenzoyl)-5-methylbenzoic acid

Reactants

COc1ccc(C(=O)Cl)cc1
4-methoxybenzoyl chloride
Cc1ccc(Br)c(C(=O)O)c1
2-bromo-5-methylbenzoic acid
—
halogen-lithium

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThis compound is obtained
  2. 2
    Otherin the following reaction

Procedure

This compound is obtained according to the procedure described in 1.1. by reacting 4-methoxybenzoyl chloride and 2-bromo-5-methylbenzoic acid after halogen-lithium exchange. It is used in crude form in the following reaction.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07423030B2uspto-grants-2008_09