Reaction #56604

ord-f41ec0659f734bcaa74cb3eeca4e0b0f

Reaction equation

COC(=O)c1ccc2nn(-c3cc(C(C)(C)C)cc(C(C)(C)c4ccc(Cl)cc4)c3O)nc2c1
5-Methoxycarbonyl2-[2-hydroxy-3-(4-chloro-α,α-dimethylbenzyl)-5-tert-butylphenyl]-2H-benzotriazole
CC(C)(O)CON1C(C)(C)CC(O)CC1(C)C
1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-4-hydroxypiperidine
CC(C)(O)CON1C(C)(C)CC(OC(=O)c2ccc3nn(-c4cc(C(C)(C)C)cc(C(C)(C)c5ccc(Cl)cc5)c4O)nc3c2)CC1(C)C
title compound
CC(C)(O)CON1C(C)(C)CC(OC(=O)c2ccc3nn(-c4cc(C(C)(C)C)cc(C(C)(C)c5ccc(Cl)cc5)c4O)nc3c2)CC1(C)C
5-[1-(2-Hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-piperidin-4-yloxycarbonyl]-2-[2-hydroxy-3-(4-chloro-α,α-dimethylbenzyl)-5-tert-butylphenyl]-2H-benzotriazole

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

5-Methoxycarbonyl2-[2-hydroxy-3-(4-chloro-α,α-dimethylbenzyl)-5-tert-butylphenyl]-2H-benzotriazole (3.89 g, 0.0081 mol) and 1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-4-hydroxypiperidine (2.41 g, 0.0098 mol) are reacted together according to the procedure of Example 1. The title compound is obtained in a yield of 2.26 g (40.2%) as a yellow solid, melting at 80-90° C., whose structure is consistent with 1Hnmr and mass spectrometry. The compound has a molar absorptivity of 17,411 l/mole cm.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07419513B2uspto-grants-2008_09