Reaction #56265

Reaction equation

2-chloroethylisothiocyanate

pyrazinamidoguanidine

N-guanidino-3,5-diamino-6-chloro-2-pyrazinecarboxamide

isothiocyanate

→

3,5-diamino-6-chloro-N-{[(2-thiazolinylamino)iminomethyl]-amino}-2-pyrazinecarboxamide

Conditions

Procedure

A process of claim 5 wherein the pyrazinamidoguanidine is N-guanidino-3,5-diamino-6-chloro-2-pyrazinecarboxamide and the isothiocyanate is 2-chloroethylisothiocyanate which yields 3,5-diamino-6-chloro-N-{[(2-thiazolinylamino)iminomethyl]-amino}-2-pyrazinecarboxamide.

Source