Reaction #55889

ord-287b883a75be461c8d84b27216c1c6b0

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

By substituting 5-methoxypipecolic acid methyl ester [prepared from 5-hydroxypipecolic acid by the procedure described in J. Chem. Soc. 429 (1945) for 5-methoxyproline] for the L-proline methyl ester in the procedure of Example 18, 2,3-dehydro-1-(3-acetylthio-1-oxopropyl)-5-methoxypipecolic acid is obtained.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04221912uspto-grants-1980_09