Reaction #55604

Reaction equation

3,4-dichloro-5-nitro-α,α,α-trifluorotoluene

→

5-Amino-3,4-dichloro-α,α,α-trifluorotoluene

Yield 78.4%

Conditions

Workup

1. 1
   Otheris reduced at room temperature in a low pressure hydrogenation apparatus

Procedure

500 ml. of an ethanolic solution containing 3,4-dichloro-5-nitro-α,α,α-trifluorotoluene (188 g. 0.72 mol), and platinum oxide (Adam's catalyst) (0.2 g.) is reduced at room temperature in a low pressure hydrogenation apparatus to give 5-Amino-3,4-dichloro-α,α,α-trifluorotoluene (129.9 g. 78%) b.p. 65°-70° C./1-2 mm.

Source