Reaction #55061

ord-e7f02d4580df49709c202e25110438c2

Reaction equation

CC(CO)COC(C)(C)C
rac.-3-tert. butoxy-2-methyl-1-propanol
BrBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1
bromine triphenylphosphine
→
CC(CBr)COC(C)(C)C
rac.-3-tert. butoxy-2-methyl-1-bromopropane
Yield 35.0%

Reactants

CC(CO)COC(C)(C)C
rac.-3-tert. butoxy-2-methyl-1-propanol
BrBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1
bromine triphenylphosphine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Reaction of rac.-3-tert. butoxy-2-methyl-1-propanol with bromine-triphenylphosphine using the procedure of Example 28 gave rac.-3-tert. butoxy-2-methyl-1-bromopropane in 35% yield as a colorless liquid, b.p. 67°-77° C. (bath temperature) (9 mm Hg.).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151205uspto-grants-1979_04