Reaction #531791

Reaction equation

Mercaptopropionic acid

Triphenylmethylchloride

→

3-(tritylthio)propionic acid

Yield 95.7%

Solvents

methylene chloride

Conditions

Workup

1. 1
   Otherwere carried out at room temperature
2. 2
   Filtrationwas gathered by filtration
3. 3
   Otherthe solid components obtained here
4. 4
   Otherwere dried under reduced pressure

Procedure

Mercaptopropionic acid 12 (3.14 g) was dissolved in 50 ml of methylene chloride. Triphenylmethylchloride 13 (8.36 g) was added to that, and 19-hour reactions were carried out at room temperature. The precipitate generated through the reactions was gathered by filtration, and the solid components obtained here were dried under reduced pressure, to form 9.86 g of 3-(tritylthio)propionic acid 14, which is a white solid.

Source