Reaction #52585

Reaction equation

5-Fluoroisatin

→

title compound

5-Fluoro-2-oxindole

Solvents

hydrazine hydrate

—

ice water

Conditions

Workup

1. 1
   Temperaturerefluxed for 1.0 hr
2. 2
   OtherThe reaction mixtures
3. 3
   FiltrationThe precipitate was then filtered
4. 4
   Washwashed with water
5. 5
   Otherdried in a vacuum oven

Procedure

5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.

Source