Reaction #51765

ord-58c3a9b280e84bafba5460fc6f8032f7

Reaction equation

CC(C)(C)c1cc(N)c([N+](=O)[O-])cc1SC#N
5-tert-Butyl-2-nitro-4-thiocyanato-phenylamine
[H][H]
hydrogen
→
CC(C)(C)c1cc(N)c(N)cc1SC#N
4-tert-Butyl-5-thiocyanato-benzene-1,2-diamine

Reactants

CC(C)(C)c1cc(N)c([N+](=O)[O-])cc1SC#N
5-tert-Butyl-2-nitro-4-thiocyanato-phenylamine
[H][H]
hydrogen

Reagents

[Ni]
Raney nickel

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

5-tert-Butyl-2-nitro-4-thiocyanato-phenylamine (prepared in Example QQ-2; 3 g, 12 mmol) was hydrogenated using Raney nickel (0.75 g) in the presence of hydrogen as described in General Method 3. MS(APCI): 222(M+H).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06852711B2uspto-grants-2005_02