Reaction #51444

Reaction equation

5-nitro-3-chloro-2,4-difluorobenzoic acid

oxalyl chloride

→

desired product

5-Nitro-3-chloro-2,4-difluorobenzoyl chloride

Solvents

dichloromethane

Conditions

Workup

1. 1
   Otherthe solvent is evaporated under vacuum

Procedure

An amount of 3.47 g (0.015 mole) of 5-nitro-3-chloro-2,4-difluorobenzoic acid and 2.03 g (0.016 mole) of oxalyl chloride are dissolved in 15 ml of dichloromethane then two drops of DMF are added. The reaction is stirred for 14 hours then the solvent is evaporated under vacuum to afford the desired product.

Source