Reaction #51318

ord-20ebdba502044513b60f4edbdc050446

Reaction equation

Nc1cc(Cl)cc(Cl)c1
3,5-dichloroaniline
CCCOC(=O)C(C)=O
n-propyl pyruvate
→
CCCOC(=O)[C@H](C)Nc1cc(Cl)cc(Cl)c1
title compound
CCCOC(=O)[C@H](C)Nc1cc(Cl)cc(Cl)c1
N-(3,5-dichlorophenyl)alanine n-propyl ester

Reactants

Nc1cc(Cl)cc(Cl)c1
3,5-dichloroaniline
CCCOC(=O)C(C)=O
n-propyl pyruvate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Following General Procedure AA above and using 3,5-dichloroaniline (Aldrich) and n-propyl pyruvate (which can be prepared by following General Procedure AO above using n-propanol in place of iso-butanol), the title compound could be prepared.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06849650B2uspto-grants-2005_02