Reaction #50719

ord-0b1f2e1c0f294ff991c72bb3ca95134c

Reaction equation

CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC
triethyl citrate
→
CCOC(=O)CC(C)=O
ethyl acetoacetate

Reactants

CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC
triethyl citrate
—
alcohol

Reagents

CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-].[Ti+4]
tetraisopropyl titanate

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherwas obtained

Procedure

In the same way as in Example 1, 60 g (0.21 mol) of tetraisopropyl titanate were reacted with 116.6 g (0.42 mol) of triethyl citrate. The mixture was freed of alcohol under vacuum and 154.6 g of a clear, pale yellow liquid was obtained.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05428103uspto-grants-1995_06