Reaction #50428

ord-d9402f9cd14742bf8acde96329546880

Reaction equation

C[C@@H]1OC(=O)[C@H](C)OC1=O
L-lactide
O=C1CCCCCO1
ε-caprolactone
CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].[Sn+2]
stannous octoate
CCCCCCCCCCCCO
lauryl alcohol
→
CC(O)C(=O)O.CCCCC(O)C(=O)O
lactic acid hydroxycaproic acid

Reactants

C[C@@H]1OC(=O)[C@H](C)OC1=O
L-lactide
O=C1CCCCCO1
ε-caprolactone
CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].[Sn+2]
stannous octoate
CCCCCCCCCCCCO
lauryl alcohol

Reagents

None

Solvents

Cc1ccccc1
toluene

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThe same procedure as in Preparation Example 3
  2. 2
    Otherwere used and that reaction

Procedure

The same procedure as in Preparation Example 3 was effected except that 1441 g (10 mols) of L-lactide, 1140 g (10 mols) of ε-caprolactone and 10 ml of a toluene solution containing 0.26 g of stannous octoate, and 5 g of lauryl alcohol were used and that reaction was carried out at 160° C. for 10 hours, thereby obtaining a lactic acid-hydroxycaproic acid copolymer (hereinafter referred to as "PCLA1").

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE034984uspto-grants-1995_06