Reaction #48139

ord-d4bb8722977941e6945f970d1a5873ce

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherIn analogy to the procedure described for the synthesis of example 6

Procedure

In analogy to the procedure described for the synthesis of example 6, the title compound was synthesized from (4,4-difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone (intermediate 1) and 3,4-dichlorophenylboronic acid. The title compound was obtained in 81% yield as yellow foam. MS (m/e): 550.2 (MH+, 100%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07745479B2uspto-grants-2010_06