Reaction #4711

ord-dffbaa0d9e044330a4d2895ea18a8ae7

Reaction equation

NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1
N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carbothioamide
O=C=Nc1ccc(Cl)cc1
4-chlorophenyl isocyanate
→
O=C(NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1)Nc1ccc(Cl)cc1
N-4-Chlorophenyl-2-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]aminothioxomethyl]-hydrazine carboxamide

Reactants

NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1
N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carbothioamide
O=C=Nc1ccc(Cl)cc1
4-chlorophenyl isocyanate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The compound is prepared by a method analogous to that of Example 9 from N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-hydrazine carbothioamide and 4-chlorophenyl isocyanate. The analytical values are summarized in Table I.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04727081uspto-grants-1988_02