Reaction #470423

Reaction equation

4′,7-Dihydroxyisoflav-3-ene

3-nitroaniline

ethanol

Formaldehyde

→

title compound

Yield 4.0%

4-(3-(3-Nitrophenyl)-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

Yield 4.0%

Conditions

Workup

1. 1
   OtherThe resulting precipitate was collected

Procedure

4′,7-Dihydroxyisoflav-3-ene (527 mg, 2.19 mmol) and 3-nitroaniline (333 mg, 2.41 mmol) were dissolved in ethanol (8 ml). Formaldehyde solution (2 ml, 0.03 mol, 37% wt) was added and the reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (35 mg, 4%).

Source