Reaction #470422

Reaction equation

4′,7-Dihydroxyisoflav-3-ene

ethanol

m-Toluidine

formaldehyde

→

title compound

Yield 48.0%

4-(3-m-Tolyl-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

Yield 48.0%

Conditions

Workup

1. 1
   OtherThe resulting precipitate was collected

Procedure

4′,7-Dihydroxyisoflav-3-ene (522 mg, 2.17 mmol) was dissolved in ethanol (8 ml). m-Toluidine (0.3 ml, 2.77 mmol) and formaldehyde solution (2 ml, 0.03 mol, 37% wt.) were added and the reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (386 mg, 48%).

Source