Reaction #45263

ord-790e1388dd254af089476ac44d4637d3

Reaction equation

CN1CCNCC1
N-methyl piperazine
ClCCBr
1-bromo-2-chloroethane
→
CN1CCN(CCCl)CC1.Cl
1-(2-chloroethyl)-4-methylpiperazine hydrochloride

Reactants

CN1CCNCC1
N-methyl piperazine
ClCCBr
1-bromo-2-chloroethane

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

N-methyl piperazine and 1-bromo-2-chloroethane are reacted using the procedure for Example OO to afford 1-(2-chloroethyl)-4-methylpiperazine hydrochloride.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07737283B2uspto-grants-2010_06