Reaction #452477

Reaction equation

acrylonitrile

2-methoxyphenylpiperazine

→

product

Yield 91.7%

3-[4-(2-Methoxyphenyl)piperazin-1-yl]propionitrile

Yield 91.7%

Solvents

ethanol

ethanol

Conditions

Workup

1. 1
   Otherthe solvent was evaporated in vacuo

Procedure

A solution of acrylonitrile (1.06 g, 20 mmol) in ethanol (50 ml) was added to a stirred solution of 2-methoxyphenylpiperazine (3.84 g, 20 mmol) in ethanol (100 ml). After 18 h, the solvent was evaporated in vacuo to give the product (4.5 g) as a white solid.

Source