Reaction #44131

ord-5df36ceb506846df86786bb67c718a03

Reaction equation

OCCc1cccc(Br)c1
2-(3-bromophenyl)ethanol
O=C1NCCO1
1,3-oxazolidin-2-one
→
O=C1OCCN1c1cccc(CCO)c1
title compound
Yield 48.0%
O=C1OCCN1c1cccc(CCO)c1
3-[3-(2-Hydroxyethyl)phenyl]-1,3-oxazolidin-2-one
Yield 48.0%

Reactants

OCCc1cccc(Br)c1
2-(3-bromophenyl)ethanol
—
amides
—
ureas
—
carbamates
O=C1NCCO1
1,3-oxazolidin-2-one

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared in 48% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 2-(3-bromophenyl)ethanol and 1,3-oxazolidin-2-one.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07732600B2uspto-grants-2010_06