Reaction #44115

ord-b2c9259d56b4414e93f286ed852a1177

Reaction equation

[BH4-].[Na+]
Sodium borohydride
CC(=O)Nc1cccc(C(=O)CN2CCN(c3cccc4nc(C)ccc34)CC2)c1
N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]acetyl}phenyl)acetamide
→
CC(=O)Nc1cccc(C(O)CN2CCN(c3cccc4nc(C)ccc34)CC2)c1
N-(3-{1-Hydroxy-2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide

Reactants

[BH4-].[Na+]
Sodium borohydride
CC(=O)Nc1cccc(C(=O)CN2CCN(c3cccc4nc(C)ccc34)CC2)c1
N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]acetyl}phenyl)acetamide

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Sodium borohydride (0.015 g, 1.6 eq) was added to a stirred solution of N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]acetyl}phenyl)acetamide

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07732600B2uspto-grants-2010_06