Reaction #43716

Reaction equation

2-fluoro-4-methoxybenzaldehyde

sodium hydride

methyl mercaptoacetate

→

title compound

Methyl6-methoxy-1-benzothiophene-2-carboxylate

Conditions

Procedure

Using 2.5 g (16.2 mmol) of 2-fluoro-4-methoxybenzaldehyde, 0.97 g (24.3 mmol) of sodium hydride (60% pure) and 1.89 g (17.8 mmol) of methyl mercaptoacetate, 3.05 g (84.7% of theory) of the title compound are obtained.

Source