Reaction #43713

Reaction equation

2,5-difluorobenzaldehyde

sodium hydride

methyl mercaptoacetate

→

title compound

Methyl5-fluoro-1-benzothiophene-2-carboxylate

Conditions

Procedure

Using 5.0 g (35.2 mmol) of 2,5-difluorobenzaldehyde, 2.11 g (52.78 mmol) of sodium hydride (60% pure) and 4.11 g (38.7 mmol) of methyl mercaptoacetate, 1.1 g (14.3% of theory) of the title compound are obtained.

Source